My Longevity Protocol by Ilhui Hernandez

“Biological systems are defined by continuous change. From cellular turnover to organismal decay, impermanence is the one constant written into every living thing.“
I am a biologist and research scientist working on the development of new molecular entities for medical purposes. I think about the body the way a systems ecologist thinks about a forest: not as a collection of parts, but as an integrated intelligence.
In ecosystems, no species exists in isolation. The influence of one ripples outward. The human body is no different. Our cells, organs, physical and mental health are deeply interconnected a principle now formalized in the field of psychoneuroimmunology, which maps the continuous dialogue between the nervous system, the immune system, and the mind.
We are the product of billions of years of evolutionary selection, 40 trillion cells, each running billions of chemical reactions per second, coordinating a volume of biological data that no model has yet fully mapped.
It is from this understanding that I built a personal longevity protocol.
The results have been measurable. I currently rank #10 globally on the Longevity World Cup trhough PhenoAge a data driven competition that gamifies biological age through blood biomarkers. According to this mathematical model my biological age is -13.3 years old.
My goal in sharing this is not to prescribe. It is to show what becomes possible when you treat your body as the remarkable, interconnected system it actually is, and to invite you to improve your own biomarkers, your cognition, your energy, and the full range of what being alive can feel like.
Does it work? The data says yes. But the more interesting question is: why and whether any part of it might work for you.
After years of studying biological systems I learn that there is no universal protocol. Your genetics, your environment, stress, adaptation, and choice your body has navigated is entirely your own. But what I can offer is a framework. Some elements of this protocol may translate directly to your life. Others may need adjusting. A few may not apply to you at all. The goal is never to copy a protocol blindly, but to understand the principles well enough to make them yours.
Current biomarkers
| Biomarker | Value | Reference Range | Status | Functional Insight |
| RDW | 12.30% | 11.5–14.5% | ✔️ | Stable red blood cell size; no anemia signal |
| hsCRP | 0.2 mg/L | <1.0 optimal | ✔️ | Very low inflammation; strong longevity marker |
| White Blood Cell Count | 3.4 K/mcL | 3.4–10.8 | ✔️ | Low-normal; common in low-inflammation states |
| Absolute Lymphocytes | 1462 cells/mcL | 1000–4800 | ✔️ | Adequate adaptive immune response |
| Glucose (fasting) | 87 mg/dL | 70–99 | ✔️ | Excellent glycemic control |
| HDL Ratio | 3.3 | <5 optimal | ✔️ | Favorable cardiovascular profile |
| Albumin | 5.0 g/dL | 3.9–5.0 | ✔️ | High-normal; strong nutritional/liver status |
| Creatinine | 0.7 mg/dL | 0.57–1.00 | ✔️ | Optimal kidney function |
| Alkaline Phosphatase | 53 U/L | 44–121 | ✔️ | Normal liver and bone metabolism |
| Phenoage | 23 | Younger physiological profile | ||
| Hormonal Biomarkers | ||||
| LH | 9.2 mIU/mL | Follicular: 2.4–12.6 | ✔️ | Balanced ovulatory signaling |
| FSH | 8.4 mIU/mL | Follicular: 3.5–12.5 | ✔️ | Healthy ovarian stimulation |
| LH:FSH Ratio | ~1.1 | ~1:1 expected | ✔️ | No PCOS pattern; coordinated axis |
| Estradiol (E2) | 32.5 pg/mL | Follicular: 12.5–166 | ✔️ | Low-normal; likely early cycle |
| DHEA-S | 134 µg/dL | 84.8–378 | ✔️ | Within range, though not high-performance |
| TSH | 2.27 µIU/mL | 0.45–4.5 | ✔️ | Normal (functional optimization may aim lower) |
| Cortisol (AM) | 16.7 µg/dL | 6.2–19.4 | ✔️ | Strong morning peak; good circadian rhythm |
| Additional info | ||||
| VO₂ Max | 45–46 ml/kg/min | Top ~10% for women 30–35 | ✔️ | Fitness: elite percentile, major predictor of lifespan |
| Resting Heart Rate | 56 bpm | 60–100 (general), <60 athletic | ✔️ | Cardiac efficiency: high, strong parasympathetic tone |
| Body Fat % | 18.30% | 18–28% (female healthy) | ✔️ | Lean, metabolically favorable |
| Muscle Mass % | 77.50% | Higher is favorable | ✔️ | Body composition: high lean mass, supports longevity |
| Metabolic Age (Withings) | 23 yrs | vs. chronological 31 | ✔️ | Younger physiological profile |
| Visia scan skin age | 27 yrs | vs. chronological 31 | ✔️ | Younger physiological profile |



Morning
Upon waking up I drink water with ginger & lemon followed by a personal supplement drink. Ginger contains gingerol, which aids digestion and reduces nausea. Lemon stimulates gastric juice production. Together they activate the digestive system, aid metabolism and support hydration after overnight fasting.
Stillness + sunlight Before the day begins, I step outside. I sit on my terrace, breath, and wait for the sun in silence. Morning light anchors the circadian clock, calibrating cortisol and setting the hormonal tone for the entire day. It is also a moment to reflect, meditate, or simply set the mindset for the day.
Coffee or matcha with collagen; 90 to 120 minutes after waking. Delay caffeine until cortisol begins its natural morning decline. This window allows the body to clear adenosine naturally and ride its peak cortisol surge (CAR).
Introducing caffeine too early blunts this effect and increases the likelihood of an afternoon energy crash.



Weekdays. Eating window opens at noon only drinks before that. This follows a time-restricted eating model, aligning intake with circadian rhythm rather than strictly cutting calories. The compressed window supports metabolic regulation, insulin sensitivity, and cellular repair processes like autophagy.
Weekends — flexible Early brunch at a café or a nutritious breakfast at home. Weekends typically involve longer runs or high-intensity training, which demand greater glycogen availability. Eating earlier supports performance and recovery.
My meals are below in Nutrition section
Workday
My work involves sitting in a desk, mobility at laboratory and and everything in between. Meetings, lunch breaks, and calls are opportunities to move rather than reasons to stay seated. I am deliberate about it: a standing desk anchors most of my workday, and I rarely let an hour pass without breaking the stillness.
Movement is woven into the rhythm of things walks during calls, grip exercises, constant posture resets. Hydration is constant, usually water with electrolytes. Posture is something I return to consciously; a straight, supported spine is not a minor detail but a long-term investment in physical resilience. Working with novel molecules in pharmaceutical development adds another layer of intentionality here, minimizing unnecessary exposure is as much a health practice as any other.
Afternoon + Evening + Night
Evenings are for community, exercise, relationships, creative work or, when needed more deep work.
Sleep is non-negotiable for me a minimum of eight hours, every night. I treat it not as rest, but as the foundation on which every other element of my health protocol is built. Sleep is when the body repairs itself, consolidates memory, regulates hormones, and resets every system that keeps us functioning at our best. Without it, nothing else works not training, not nutrition, not cognitive performance. It is the most powerful and underutilized tool in longevity.
I also listen carefully to what my body needs beyond that baseline. I adjust my sleep duration based on training load and the demands of my menstrual cycle both of which have a profound and measurable impact on recovery.
To improve sleep quality I keep the room cool between 60 and 67°F (15–19°C) I use an eye mask. I track sleep with a Whoop and an Oura ring, though I hold data and intuition in equal regard. Numbers are useful; but knowing your own body trough intuition is best.
I avoid screens in the hour before bed, or use blue-light blocking glasses when that is not possible. Blue light suppresses melatonin secretion by inhibiting the pineal gland delaying sleep onset and reducing overall sleep quality.
Dinner About three hours before sleep. Based on glucose tracking, I sometimes include a small snack with healthy fats in the evening, as extended overnight fasting does not appear optimal for my physiology.
Training
Afternoon reset After work I train. I do dry sauna three times per week at around 70°C-100°C, 158-212° ideally 20 min. Apparently this are the conditions to benefit the most of sauna.
Framework inspired by Nordic endurance culture The week includes VO2 max intervals, Zone 2 cardio, strength training, resistence training, mobility, flexibility, and injury prevention. I alternate this workouds trough the week, and when I feel l like resting I simply rest. As example:
Monday: Lower body (resistence training)
Tuesday: Core and streching exercises+ HIIT (4×4 nordic intervals)
Wednesday: Run outdoors enjoying nature
Thursday Upper body( resistence training)
Friday Injury prevention exercises.
Saturday or sunday : Long run, hiking, outdoors sports or usual trail running (8-15km).
Trail running has so many benefits but my favourite one is the fact that it literally rewires your brain to become more adaptable. It enhances neuroplasticity which is basically what keeps your brain sharp, adaptable and resilient as you age.
It supports memory, coordination and learning which all things that tend to decline over time if not used.It also stimulates your brain’s ability to change and adapt. As you decide where to step and how to balance in real time, you strengthen neural pathways and improve how your brain responds to movement. -You are literally rewiring your brain to become more adaptable-.



Resistance training naturally stimulates collagen production one of the reasons building and maintaining muscle is central to any longevity protocol, not just an aesthetic choice.
Nature
Forests and natural environments expose us to phytochemicals that strengthen our inmune system and benefit the microbiome skin, gut, and beyond. Nature reduces stress and restores something no supplement can replicate.
Hormesis as a foundational habit.



Hormesis is the principle that a measured dose of stress one that is neither chronic nor damaging can make us stronger. It is the sweet spot between discomfort and growth, and it is one of the most meaningful foundations someone can built a mindset around .

HIIT exercise, sauna, ice swimming, cold plunges, and contrast therapy are its clearest expressions. I have practiced them in every form available to me. But beyond the physical, hormesis has become a philosophy: I genuinely believe that discomfort is where the most meaningful growth happens physically, mentally, spiritually.
Skin
Microneedling: monthly, followed by peptide-based creams alternating with Nordic retinoids and formulas rich in Arctic berry extracts, Hialuronic acid, collagen and other active ingrendientes such as those in edelweiss.



Red light therapy three times per week see my protocol here: SKIN PROTOCOL
NUTRITION
The Foundation 🥦
- Vegetables, legumes, and pulses anchor every meal, typically structured as a 50/50 balance with either high-quality animal protein or plant-based alternatives like tofu and tempeh.
- Sardines are a staple protein source due to their favorable omega-3 profile and lower heavy metal accumulation; poultry and fish are included regularly, with occasional additions of grass-fed meat or wild game.
- Cruciferous vegetables such as broccoli, cauliflower, bok choy, and sprouts are prioritized for their sulforaphane and myrosinase content, supporting detoxification pathways and anti-inflammatory signaling.
- Purple sweet potatoes are included for their high polyphenol density and incredibly nutrient-dense profile.
- Shiitake mushrooms contribute bioactive compounds like lentinan for immune modulation and eritadenine for lipid regulation.
- Beluga lentils and forbidden rice are selected for their elevated anthocyanin content compared to conventional varieties.
Fats & Grains
- Extra virgin olive oil serves as the primary fat source, occasionally complemented by avocado.
- Apple cider vinegar is consistently added to salads to support glycemic control.
- When grains are included, whole grain options are chosen, with a preference for rye due to its lower glycemic index and higher fiber content.
Fermented Foods
- A fermented food is included in every meal as a non-negotiable for microbiome support.Rotating sources include kefir, Greek yogurt, labneh, kombucha, sauerkraut, beet kvass and kimchi.
Hydration & Drinks
- Ginger with lemon in the morning supports digestion and motility.
- Greek mountain tea is one of the best sources of polyphenols and is gentle on the digestive system (Ikarian residents drink this often).
- Kombucha and beet kvass are used as functional beverages to support gut health, liver function, and circulation.
- Coffee or matcha, typically two to three servings per day, for polyphenols and cognitive performance.
- Sparkling water
High-Impact Add-Ons
- Wild blueberries, bilberries, nordic dried berries, pomegranates, dark chocolate, capers, nuts, seeds, LOTS OF SEEDS (chia, lindseed, flaxseed, hemp seed) nutritional yeast, bone broth,
Functional Spices
- Rosemary for its antioxidant and antimicrobial compounds.
- Curcumin for its potent anti-inflammatory and signaling effects.
- Mexican oregano for antifungal and anti-inflammatory properties.
- Saffron for mood regulation and cognitive support.
What I Avoid, Minimize
Fast Food, Never soda.
Refined ingredients and additives such as emulsifiers, stabilizers, thickeners, and artificial colorants (only in supplements, collagen powders, etc)
Low-nutrient greens, like iceberg lettuce, are in favor of more mineral-dense options.
Guilty pleasure? A glass of good wine.



SUPPLEMENTS
Backed up by science
- VSupplements:
- The supplements I use are personalized to my physiology and needs, based on data from blood tests and genetic analysis.
- Supplements:
- Core metabolic compounds (longevity mix)
- • Calcium Alpha-Ketoglutarate (Ca-AKG) (longevity mix)
- • Creatine Monohydrate (longevity mix)
- • Omega-3 (Nordic naturals)
- • CoQ10 ( Thorne)
- Amino acids
- • Glycine (longevity mix)
- • Taurine (longevity mix)
- • L-Lysine (longevity mix)
- • L-Theanine (longevity mix)
- Antioxidants
- • Reduced Glutathione (longevity mix)
- • Vitamin C (Ascorbic Acid) (Naturewise)
- Structural / skin support
- • Sodium Hyaluronate (Hyaluronic Acid) (longevity mix)
- • Collagen (Ancient and Brave)
- Minerals
- • Magnesium Citrate (longevity mix)
- • Calcium (longevity mix)
